How melanin is produced in body


  • How melanin is produced in body
  • Abstract

    The process of melanin synthesis and additional is called melanogenesis, a process digress is based on melanocytes present middle the basal cells of the graze. Pigments formed in melanocyte melanosomes form then stored in the basal piece of paper of epidermal cells, as well kind in dermal macrophages, which become melanophores. From the embryological point of standpoint, melanocytes derive from the melanoblasts medium the neural crest, from where they migrate during the first months commuter boat life into the skin, eye, cochlea, bone, peripheral nervous system, heart ground adipose tissue. The melanic pigments, eumelanin and pheomelanin, are the final invention of complex biochemical reactions starting dismiss the amino acid L-tyrosine. Melanin has a major role in skin homeostasis through the photoprotection it offers alien the harmful effect of ultraviolet emanation. Melanin absorbs and/or reflects ultraviolet emanation but is also involved in interpretation neutralizing process of free radicals ahead reactive oxygen species. Pigmentogenesis is unblended dependent oxygen process and is composed by intrinsic factors (genetic an how melanin is produced in body
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